Inositol is a naturally occurring substance that is postulated to improve insulin sensitivity by enhancing signal transduction via an alternative pathway for insulin action. Also work better in pregnancy induced diabetes.
Chromium supplementation in women with PCOS resulted in significant improve in insulin sensitivity, decreasing serum triglycerides VLDL and cholesterol concentrations.
Alpha Lipoic Acid is known to have antioxidant and anti-inflammatory properties, useful in managing insulin resistance and its complications, treat neuropathy, improve insulin sensitivity, lower blood sugar and cholesterol.